Aplastic anemia disease is a condition that occurs when a person stop producing enough fresh and new blood cells. The condition leaves a person fatigued and more prone to infections &uncontrolled bleeding. Allogenic transplant is a procedure which is needed to be done in patients suffering from aplastic cell anemia in which stem cells are received from HLA matched donor and they are then infused to the recipient for the marrow to start forming/producing normal cells and stop forming abnormal blood cells which are not normal as they are in a normal human being. This procedure is offered to patients who are require regular and frequent blood transfusion and ONLY for those patients who are considered eligible for stem cell transplant considering all the clinical aspects of the patient. Please note that all the patients suffering from aplastic cell anemia are not candidates of bone marrow transplant. Some of the Patients do well with ATG therapy offered at top hospitals like BLK-MAX Super Speciallity Hospital, Apollo Hospitals, Fortis Hospitals, Artemis Hospitals and American Oncology Institute etc.
Now let us discuss about the donor who is searched from direct biological siblings of the patient, chances of getting a matched donor in direct siblings are very high, biological parents of the patient are not matched, they are mostly half matched or slightly over half matched but considered as half matched donors by the doctors. In case there is no matched donor in the siblings that are available to donate. The bone marrow transplant specialists search from donors from the international bone marrow registry which is a lengthy procedure to follow but when the patient do not have a donor, the only choice left is to search for a donor from international registry of stem cell donors. Once the Haematologists identify a matched-donor, there is need for making arrangements for stem cells to be transported from place of donor to the place of recipient(Patient).
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